COSRX - 5 PDRN Collagen Intense Vitalizing Serum 100ml

COSRX 5 PDRN Collagen Intense Vitalizing Serum combines five types of PDRN with 200Da low molecular collagen — a lightweight all-in-one serum for skin that looks flat and tired.

Five PDRN sources in one formula

Salmon, centella asiatica, rice, lactobacillus and sea grape. Most PDRN products use one source; drawing from five broadens the ingredient story, and the plant and microbial versions reflect where the category is heading in 2026.

200Da collagen — what the number means

Daltons measure molecular weight, and 200Da is very low for collagen. Worth being honest about what topical collagen does: molecules are too large to travel into deeper skin layers regardless of size. What they do genuinely well is hold water at the surface, which makes skin look plumper and softens the appearance of fine dryness lines.

Eight types of hyaluronic acid

Different molecular weights sit at different levels — larger molecules hold water at the surface, smaller ones distribute through the upper layers. A spread of eight covers both ends.

Niacinamide, panthenol and peptides

Niacinamide for evenness and dullness, panthenol for soothing, peptides for the look of firmness. It’s a genuinely full formula rather than one active with filler.

Lightweight, layers cleanly

The texture absorbs without tackiness, so it sits under moisturizer and sunscreen without disrupting anything else in your routine.

Realistic expectations

Hydration and a plumper look show up quickly. Anything to do with fine lines takes months of consistent use — and daily sunscreen matters more for that than any serum does.

Frequently asked questions

What is PDRN?

Polydeoxyribonucleotide — originally from salmon DNA, now also produced from plant and microbial sources. One of the defining Korean skincare ingredients of 2026.

Is this vegan?

No — one of the five PDRN sources is salmon, and the collagen is animal-derived.

Where does it go in my routine?

After toner, before moisturizer. Pat into slightly damp skin, then seal with a cream.

Can I use it with retinol?

Yes — a hydrating serum layered around retinol is a common way to keep skin comfortable. Introduce one new active at a time.

How long does 100ml last?

Serums are used sparingly, so expect several months of twice-daily use. That’s a generous size for the category.

Pairs well with

Prep with the 5 PDRN B5 Toner. Browse PDRN, collagen, Korean serums and firming picks.